The 2025 Panigale V4 is Ducati's flagship superbike, completely redesigned for its sixth generation. Its styling looks back to the legendary Ducati 916, with double "V" daytime running lights and a cleaner fairing that hides the main air intake. The biggest change is the switch from Ducati's signature single-sided swingarm to a double-sided swingarm, taken from its WorldSBK race bike for better grip and feedback.

Its 1,103 cc V4 makes 216 hp. That's slightly less peak power than the BMW M 1000 RR, but it has more torque, about 121 Nm against 113 Nm, and the V4's famous bark. The V4 S is the one most enthusiasts choose, thanks to Öhlins semi-active suspension and lighter forged wheels. Ducati's electronics, including the new Race eCBS braking, make that power easier to use on the road and on track.